ZPP 206M


  • Automatic sample insertion
  • Uses whole blood with no sample preparation
  • Digital readout in approximately 5 seconds
  • Internal reference standard
  • Internal low level control
  • No volume measurement required
  • No false negatives
  • Minimum effects of deoxyhemoglobin
  • Filter front surface fluorometer
  • Narrow band interference filters
  • ZPP red blood cell cryopreserved
    controls stable for 3 months frozen
  • One year warranty on parts and labor

Download Brochure   Iron Metabolism Disorders  References


Cover Glass

AVIV 25mm x 25mm, pre-cleaned (disposable) cover glass are packed 10 inner boxes of 100 cover glass per box.(Total – 1,000 cover glass per case). Quantity discounts available.
Part #9999-91466

Calibrator Sets

Easy to use 2 level set (low, high) ZPP red blood cell calibrators make calibration of your instrument simple. Cryopreserved calibrators remain stable up to one month when stored at -20°C. Target values are the concensus of the Pb/EPPTP of the Centers for Disease Control, N.Y.
Part #9999-112562

Control Sets

Easy to use 3 level set (low, medium, high) ZPP red blood cell controls make quality control of your instrument simple. Cryopreserved controls remain stable up to three months when stored at -20°C.
Part #9999-40839


Step 1
The model 206M provides quick and accurate measurement of the ratio of zinc protoporphyrin to heme in whole blood. No volume measurement is needed. The sample is optically dense and front surface illumination is used. As little as 5 x 10-12 grams of zinc protoporphyrin can be detected in a single drop of whole blood. Simply puncture a finger, toe or ear lobe which has been cleaned with alcohol.

Step 2
Place a glass cover slide (AVIV No. 1, 25mm sq.) into the sample holder. A drop of whole blood is then placed in the center of the cover slide, sufficient to cover the aperture. No additional preparation is needed and no volume measurement is required.

Step 3
With the sample in place, operate the Model 206M by simply depressing the measure button located on the front of the instrument. The instrument will pause for a second to calibrate itself, automatically draw the sample holder with the whole blood sample into the measuring compartment, analyze the sample, display the results and return the sample for easy disposal. Although the instrument always measures the molar ratio of ZPP to Heme, the instrument can be ordered calibrated to display this result in any one of several units. Many instruments in the USA are calibrated to display weight/ volume concentration units using assumed hematocrits as specified by OSHA (ZPP, Hct 42) or CDC (equivalent EP, Hct 35). These calibrations are fully acceptable to the respective agencies. We strongly recommend the use of molar SI units µmole/mole Heme or µg ZPP/gram Hb for all other purposes.

Related Links

American Family Physician
Joint Centers for Sickle Cell and Thalassemic Iron Metabolism Disorders
Transient Erythroporphyria of Infancy

Office of Health, Safety and Security:
Initial Blood Lead Monitoring
Lead Standard: Trigger Levels
Zinc Protoporphyrin Criteria Under 1926.62
Respirator Fit Factors and Post Exposure ZPP Testing

Occupational Safety and Health Administration:
Medical surveillance guidelines – 1910.1025 App C
Medical Surveillance Guidelines – 1926.62 App C
Occupational Safety and Health Standards for Shipyard Employment. – 58:35512
01/01/1993 – Lead Exposure in Construction (#6 of 6) – Medical Surveillance

World Health Organization:
Assessing the Iron Status of Populations
Lead: Children’s Health and the Environment

Worldwide Sales Distributors

Aviv has distributors worldwide that can help you purchase, or repair, a ZPP 206M Hematofluorometer. Click here to view the list.